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Mechanistically, it has been observed that GSTP1-1 binds, in its monomeric form, both c-Jun and JNK, thus forming an heterotrimeric complex that inhibits the phosphorylation of c-Jun by JNK

albicans are recognized by Dectin-1, they activate NF-B and IRF through the Syk/CARD9/Bcl10/MALT1 axis, driving the secretion of IL-1, IL-6, and IL-23, thereby inducing the production of IL-17A/F and IL-22 by Th17 cells, recruiting neutrophils and enhancing the epithelial barrier, forming the core anti-fungal defense line (Swidergall, 2019)

What is LL-37

The three peptide chemicals are joined in sequence by peptide linkages